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Updated: Jul 16, 2026

Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding
10:50

Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding

Published on: September 15, 2010

大分子拥挤对HIV-1蛋白酶内部动态的影响

David D L Minh1, Chia-en Chang, Joanna Trylska

  • 1Department of Chemistry & Biochemistry, Center for Theoretical Biological Physics, University of California at San Diego, La Jolla, California 92093-0365, USA. dminh@mccammon.ucsd.edu

Journal of the American Chemical Society
|May 4, 2006
PubMed
概括

大分子拥挤显著减少了HIV-1蛋白酶的开放,影响了酶活性. 这一发现表明,拥挤在病毒生命周期中起着关键作用.

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Inhibitors of Virion Maturation and Assembly01:19

Inhibitors of Virion Maturation and Assembly

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