在心内分离的患者中,通过静脉输入的节奏指导和全身血栓栓塞:一个多中心研究
Paul Khairy1, Michael J Landzberg, Michael A Gatzoulis
1Adult Congenital Heart and Electrophysiology Services, Montreal Heart Institute, Montreal, Canada. paul.khairy@umontreal.ca
Circulation
|May 17, 2006
概括
通过静脉输入的导体显著增加了心内转移患者的全身血栓栓塞的风险,超过了危险的两倍. 这一发现突出了这一患者群体中选择的关键考虑因素.
科学领域:
- 心脏病学 心脏病学
- 医疗器械 医疗器械
- 血栓栓塞瘤研究研究
背景情况:
- 对于需要心脏电子设备的患者来说,心脏内切换存在独特的风险.
- 系统性血栓栓塞 (血栓) 的特定风险与静脉输送的线索在心脏内转移患者之前是未知的.
研究的目的:
- 根据所使用的心脏的类型来量化心内冲路患者系统性血栓栓塞的风险.
- 在这个特定的患者队列中确定系统性血栓栓塞的独立预测因子.
主要方法:
- 这是一项多中心的回顾性队列研究,涉及202名心内短路患者.
- 患者被分为三组:静脉输血导入 (n=64),心上导入 (n=56) 和没有导入 (n=82).
- 随访数据收集用于跟踪系统性血栓栓塞的发生,随访时间的中位数从7.3年到17.0年不等.
主要成果:
- 系统性血栓栓塞发生在15.6%的透静脉线患者中,8.9%的表心线患者中,11.0%的无线患者中.
- 通过静脉输入的被确定为系统性血栓栓塞的独立预测因子 (危险比率[HR],2.6;P=0.0265).
- 高龄,心房动/动和正在进行的脑膜切除术也是通过静脉输血的患者的重要危险因素.
结论:
- 通过静脉输入的导体与心内短路患者的全身血栓栓塞的风险增加两倍以上有关.
- 这些发现强调了考虑类型的重要性,在管理心脏内避路患者时,以减轻血栓栓塞的风险.
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