相关实验视频

Updated: Jul 19, 2026

Using RNA-interference to Investigate the Innate Immune Response in Mouse Macrophages
12:47

Using RNA-interference to Investigate the Innate Immune Response in Mouse Macrophages

Published on: November 3, 2014

自主反应性B细胞对与RNA相关的抗原的反应是由于TLR7基因重复导致的

Prapaporn Pisitkun1, Jonathan A Deane, Michael J Difilippantonio

  • 1Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Rockville, MD 20852, USA.

Science (New York, N.Y.)
|May 20, 2006
PubMed
概括

带有Y结合的自身免疫加速器 (Yaa) 位点的B细胞由于增加了托尔类受体7 (TLR7) 表达,对核抗原有偏见. 这突显了Y染色体基因重复如何影响自身免疫性疾病. 关键词:自身免疫,B细胞,雅雅部位,TLR7,核抗原.

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