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Updated: Jul 20, 2026

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在服用口服铁化剂L1的患者中致命的系统性红斑狼

J Mehta, S Singhal, R Revankar

    Lancet (London, England)
    |February 2, 1991
    PubMed
    概括

    No abstract available in PubMed .

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    Leishmaniasis is a widespread parasitic disease caused by several Leishmania species. It affects millions of people each year and remains a major public health problem in endemic regions. First-line treatment relies on pentavalent antimonials, including meglumine antimoniate and sodium stibogluconate. Even so, how these drugs work has not been fully clear, especially their interaction with parasite-specific biochemical pathways. One key target is trypanothione reductase (TR), an enzyme that...