链接的DNA标记物用于家族腺瘤多重症的症状前诊断

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Updated: Jul 6, 2026

Digital Polymerase Chain Reaction Assay for the Genetic Variation in a Sporadic Familial Adenomatous Polyposis Patient Using the Chip-in-a-tube Format
05:58

Digital Polymerase Chain Reaction Assay for the Genetic Variation in a Sporadic Familial Adenomatous Polyposis Patient Using the Chip-in-a-tube Format

Published on: August 20, 2018

M G Dunlop1, A H Wyllie, C M Steel

  • 1University of Edinburgh Department of Clinical Surgery, UK.

Lancet (London, England)
|February 9, 1991
PubMed
概括

使用DNA探针进行基因检测,准确地确定了患有家族腺瘤多重症 (FAP) 高风险的个体. 这种综合风险分析可以显著改善FAP查计划.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...