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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

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过渡性缺血性发作和小血管疾病. 荷兰TIA研究小组

L J Kappelle¹, J C van Latum, P J Koudstaal

¹University Department of Neurology, Utrecht, Netherlands.

Lancet (London, England)

|February 9, 1991

概括

过渡性脑性缺血 (TCI) 患者患有缺口性心脏病发作,通常会出现特定的单边症状. 这表明缺口性TIA可能会先于皮质心脏病发作或有更好的预后.

科学领域:

神经学神经学
放射学放射学是一门学科.
脑卒中医学脑卒中医学

背景情况:

暂时性脑缺血 (TCI) 是一种关键的神经事件.
对于预后来说,区分缺口性心脏病和皮质性心脏病发作是必不可少的.
计算机断层扫描 (CT) 在诊断脑梗塞方面发挥着关键作用.

研究的目的:

在TCI中调查患者病史和心脏病发作类型之间的关系.
为了确定特定的症状是否预示着缺口性心脏病发作.
为了比较CT上可见心脏病发作和没有心脏病发作的患者中缺口症状的频率.

主要方法:

对606名TCI患者的临床病史和CT扫描进行了回顾性分析.
排除后缺血病发作的可能性.
对有或没有相关心脏病发作的CT患者病史的比较.

主要成果:

确定了79个相关心脏病发作:46个腔 (58%) 和33个皮质.
缺口性症状对缺口性心脏病发作有0.74的积极预测值.
在CT上没有心脏病发作的TCI患者中,64%报告了缺口症状,高于其他研究.

结论:

缺口症状与缺口心脏病发作有很强的关联.
缺陷性TIA可能有更好的预后或先于皮质中风.
有时皮质梗塞可能会在没有预警症状的情况下发生.

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Transient Ischemic Attack l: Introduction

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