胰岛素高血压和微血管性心痛 ("X综合征")
J D Dean1, C J Jones, S J Hutchison
1Department of Cardiology, University of Wales College of Medicine, Cardiff, UK.
Lancet (London, England)
|February 23, 1991
概括
与健康个体相比,患有微血管性心痛的患者在葡萄糖负载后显示出更高的胰岛素水平. 这表明,胰岛素水平升高可能导致冠状动脉微血管功能障碍.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 代谢研究研究 代谢研究
背景情况:
- 微血管冠状动脉功能障碍是心痛的一个重要原因.
- 胰岛素在微血管冠状动脉功能障碍中的作用尚不清楚.
研究的目的:
- 在患有微血管性心痛的患者中研究葡萄糖和胰岛素反应.
- 将这些反应与健康受试者的反应进行比较.
主要方法:
- 研究了11名患有微血管性心痛的患者和11名健康对照.
- 这两组都接受了葡萄糖负载.
- 测量葡萄糖和胰岛素水平.
主要成果:
- 患有微血管性心痛的患者表现出刺激性高胰岛素血症.
- 这种高胰岛素血症明显高于对照组.
结论:
- 胰岛素度增加与冠状动脉微血管功能障碍有关.
- 胰岛素可能在微血管性心痛的病理生理学中发挥作用.
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