西非的传播的玻利利病
J F Trape1, J M Duplantier, H Bouganali
1Orstrom, Dakar, Senegal, Africa.
Lancet (London, England)
|February 23, 1991
概括
在塞内加尔,导致传播的复发性发烧的Borrelia感染很普遍,影响人类和动物. 这项研究突出显示,玻利利病是西非农村地区的重大健康问题.
科学领域:
- 医学昆虫学 医学昆虫学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 由Borrelia crocidurae引起的传播复发性发烧 (TBRF) 很少在西非报告.
- 对于该地区的TBRF存在有限的流行病学数据.
- 玻利利病可能是农村人口中未被确诊的发烧原因.
研究的目的:
- 确定Borrelia感染在人类中存在的发烧源不明和在塞内加尔的一般门诊患者中的流行率.
- 评估小哺乳动物中Borrelia感染的流行率,为螺旋体提供潜在的储存库.
- 调查塞内加尔雷病的分布和发病率.
主要方法:
- 在1340名患有发烧的儿童和随机选择的门诊患者中检查Borrelia的厚血涂抹.
- 在小哺乳动物 (动物和食虫动物) 中通过直接涂抹检查和白小鼠腹腔内接种Borrelia感染的评估.
- 在不同年龄组的儿童中分析波雷利亚发病率.
主要成果:
- 在接受检查的儿童中,Borrelia被检测到0.9%,在老年年龄组 (10-14岁) 的患病率更高.
- 在461只野生动物和昆虫食动物中,65只被证实患有菌病,当通过小鼠接种 (33.3%) 与直接涂抹 (14.1%) 评估时,感染率更高.
- 在塞内加尔不同地区的多个动物物种中观察到波雷利亚感染.
结论:
- 麻疹病在塞内加尔具有广泛的分布和高发病率,这表明它是一个重要的公共卫生问题.
- 小型哺乳动物,特别是动物,是该地区Borrelia的重要储存库.
- 波雷略病可能是西非农村地区的主要致病原因,需要提高认识和诊断努力.
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