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相关概念视频

What is Natural Selection?01:32

What is Natural Selection?

Natural selection is an evolutionary process in which individuals with survival-promoting traits reproduce at higher rates. These favorable traits become more common within a population or species. Naturally selected traits initially arise via random genetic mutations. In order for selection to occur, there must be variation within a population, the trait controlling the variation must be heritable, and there must be an evolutionary advantage for variation in the trait.The Theory of Natural...
Limits to Natural Selection01:38

Limits to Natural Selection

Organisms that are well-adapted to their environment are more likely to survive and reproduce. However, natural selection does not lead to perfectly adapted organisms. Several factors constrain natural selection.For one, natural selection can only act upon existing genetic variation. Hypothetically, redtusks may enhance elephant survival by deterring ivory-seeking poachers. However, if there are no gene variants—or alleles—for redtusks, natural selection cannot increase the prevalence of...
Genetic Drift03:33

Genetic Drift

Natural selection—probably the most well-known evolutionary mechanism—increases the prevalence of traits that enhance survival and reproduction. However, evolution does not merely propagate favorable traits, nor does it always benefit populations.Life is not fair. A deer grazing contentedly in a field can have her meal cut tragically short by a bolt of lightning. If the doomed doe is one of only three in the population, 1/3 of the population’s gene pool is lost. Random events like this can...
Types of Genetic Transfer Between Organisms02:18

Types of Genetic Transfer Between Organisms

Genetic transfer occurs when genetic information is passed from one organism to another. It occurs via two mechanisms: vertical gene transfer and horizontal gene transfer. Vertical gene transfer occurs when genetic information is transferred from one generation to the next, which happens much more frequently than horizontal gene transfer. Both sexual and asexual reproduction are forms of vertical gene transfer, where one or more organisms pass some or all of their genome onto their progeny.
Generalization, Discrimination, and Extinction01:24

Generalization, Discrimination, and Extinction

Generalization, discrimination, and extinction are key concepts in operant conditioning that influence how behaviors are learned and maintained.
Generalization occurs when a behavior reinforced in one context is performed in similar situations. For instance, a student who studies diligently for calculus and receives excellent grades might apply the same study habits to psychology and history, expecting similar results. Generalization shows how learning in one setting can influence behavior in...
Natural and Artificial Concepts01:24

Natural and Artificial Concepts

In psychology, concepts can be divided into two categories: natural and artificial. Natural concepts are formed through direct or indirect experiences. For example, consider the concept of snow. If you live in a place with regular snowfall, such as Essex Junction, Vermont, you know snow through direct experiences. You’ve seen it fall, touched it, shoveled it, and played in it. You recognize its texture, appearance, and even its smell. In contrast, if you live on an island like Saint Vincent in...

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相关实验视频

Updated: Jul 14, 2026

Large-scale Reconstructions and Independent, Unbiased Clustering Based on Morphological Metrics to Classify Neurons in Selective Populations
12:27

Large-scale Reconstructions and Independent, Unbiased Clustering Based on Morphological Metrics to Classify Neurons in Selective Populations

Published on: February 15, 2017

一个高效扩展的类别的不自然的基对.

Aaron M Leconte1, Shigeo Matsuda, Floyd E Romesberg

  • 1Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Journal of the American Chemical Society
|May 25, 2006
PubMed
概括

研究人员开发了一种新的选方法,用于为合成生物学和生物技术寻找高效的疏水性非自然基因对. 这一发现提升了创造具有扩展能力的新型核酸的潜力.

科学领域:

  • 生物化学 生物化学
  • 分子生物学分子生物学
  • 合成生物学 合成生物学

背景情况:

  • 第三个DNA基对的开发对于合成生物和核酸生物技术的应用至关重要.
  • 疏水性非自然核基为创建这种对提供了可行的方法,但在有效扩展方面面临着挑战.
  • 效率低下的扩展,即不自然的基对之后的合成,阻碍了这些分子的实际应用.

研究的目的:

  • 开发一种简单的选方法,用于表征许多未表征的异基基对.
  • 为了识别具有增强延伸效率的新型非自然基对.
  • 了解影响非自然基对有效延伸的因素.

主要方法:

  • 设计了一种高通量选试验,以评估各种异基对的延伸效率.
  • 动力分析被用来进一步描述有前途的非自然基对的表现.
  • 系统地选了以前未经表征的异基基对.

主要成果:

  • 一种新的选方法成功地表征了大量的异质基对.
  • 与之前报告的对相比,确定了一类非自然基对,其延伸效率高于之前报告的对.
  • 该研究确定了具有显著改善延伸能力的特定疏水性非自然基对.

更多相关视频

Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group
07:49

Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group

Published on: August 16, 2017

Identifying Amino Acid Overproducers Using Rare-Codon-Rich Markers
10:41

Identifying Amino Acid Overproducers Using Rare-Codon-Rich Markers

Published on: June 24, 2019

相关实验视频

Last Updated: Jul 14, 2026

Large-scale Reconstructions and Independent, Unbiased Clustering Based on Morphological Metrics to Classify Neurons in Selective Populations
12:27

Large-scale Reconstructions and Independent, Unbiased Clustering Based on Morphological Metrics to Classify Neurons in Selective Populations

Published on: February 15, 2017

Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group
07:49

Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group

Published on: August 16, 2017

Identifying Amino Acid Overproducers Using Rare-Codon-Rich Markers
10:41

Identifying Amino Acid Overproducers Using Rare-Codon-Rich Markers

Published on: June 24, 2019

结论:

  • 开发的选方法有效地识别了可行的非自然基对.
  • 鉴定到的非自然基对显示出前所未有的扩展效率,为新的生物技术应用铺平了道路.
  • 进一步的动力分析补充了选,以阐明有效扩展的机制并指导未来的设计.