病患者的一级亲属的牙面膜缺陷
1Department of Clinical Sciences, University of Tampere, Finland.
Lancet (London, England)
|March 30, 1991
概括
牙面膜缺陷可能表明亲属患有腹腔疾病的风险. 虽然并不是所有的病变都患有这种病症,但这些变化可以帮助查心脏病.
科学领域:
- 胃肠病学 胃肠病学
- 遗传学 是一个遗传学.
- 牙科 牙科是指牙科的专业.
背景情况:
- 结肠病通常会影响患者的亲属.
- 牙面膜缺陷在一些乳患者中被观察到.
研究的目的:
- 为了研究牙变化作为查工具,在健康的亲属中检查腹腔疾病.
- 评估牙面膜病变与腹腔疾病之间的关联.
主要方法:
- 牙科检查了56名胆固醇病患者的健康一级亲属.
- 小肠活检用于组织学确认.
- 与HLA-DR3和扩展的单元类型的关联分析.
主要成果:
- 在56名亲属中,有25人表现出乳类型的乳损伤.
- 所有7名证实患有心脏病的亲属都有膜病变.
- 乳缺陷可以独立于小肠变化发生.
- 结肠病类型的牙变化与HLA-DR3有很强的联系.
结论:
- 牙面膜检查可以作为一种有用的初步查方法,用于在危险的亲属中发现腹腔疾病.
- 质缺陷的存在需要进一步调查乳病,即使没有确定的小肠变化.
- 在这个人群中,HLA-DR3与乳类型的牙变化有关.
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