相关实验视频
Updated: Jun 30, 2026

10:33
Research and Development of High-performance Explosives
Published on: February 20, 2016
作用电位必须容纳来唤起发射器释放
1Department of Molecular and Cell Biology, University of California, Berkekey 94720.
Nature
|March 14, 1991
概括
神经递质的释放依赖于内部,而不仅仅是电压. 提高内部没有流入,即使没有动作潜力,触发释放,支持神经元信号的假说.
科学领域:
- 神经科学是一个神经科学.
- 细胞生物学 细胞生物学
- 神经传递的神经传递
背景情况:
- 两个假设解释了神经递质释放:假说和电压假说.
- 假设假设,离子在脱极化开放通道后触发释放.
- 电压假设表明,脱极化直接通过电压诱导的蛋白质构造变化在的存在下触发释放.
研究的目的:
- 调查在神经肌肉结节释放神经递质的基础机制.
- 要区分假说和电压假说.
主要方法:
- 在没有的林格溶液中使用或离子阻止的流入.
- 使用中的化合物提高了内部度 ([Ca2+]i).
- 发射器释放在神经肌肉结处进行测量.
- Fura-2用于测量细胞内水平.
主要成果:
- 当的流入被阻断时,单独增加的内部就足以导致神经递质释放.
- 在这些条件下,预突触作用电位不会影响发射器释放.
- 结果表明,当内部含量高时,脱极化并不直接需要触发释放.
结论:
- 这些发现强烈支持神经递质释放的假说.
- 神经元信号传递机制主要是由细胞内动态驱动的.
- 电压通道在启动依赖的释放过程中起着至关重要的作用.
相关概念视频
Equipotential Surfaces and Conductors
For a conductor in which all charges are at rest, the conductor's surface is equipotential. The electric field is always perpendicular to equipotential surfaces. Therefore, in a conductor with static charges, the electric field just outside the conductor is always perpendicular to the conductor's surface. Any tangential component of the electric field will cause charges to move inside the conductor, which will violate the electrostatic nature of the system. In an electrostatic situation, if a...
Motional Emf
Magnetic flux depends on three factors: the strength of the magnetic field, the area through which the field lines pass, and the field's orientation with respect to the surface area. If any of these quantities vary, a corresponding variation in magnetic flux occurs. If the area through which the magnetic field lines are passing changes, then the magnetic flux also changes. This change in the area can be of two types: the flux through the rectangular loop increases as it moves into the magnetic...
Induced Electric Fields
The fact that emfs are induced in circuits implies that work is being done on the conduction electrons in the wires. What can possibly be the source of this work? We know that it’s neither a battery nor a magnetic field, as a battery does not have to be present in a circuit where current is induced, and magnetic fields never do any work on moving charges. The source of the work is in fact an electric field that is induced in the wires. For example, if a stationary conductor is placed in a...
Induced Electric Fields: Applications
An important distinction exists between the electric field induced by a changing magnetic field and the electrostatic field produced by a fixed charge distribution. Specifically, the induced electric field is nonconservative because it does not work in moving a charge over a closed path. In contrast, the electrostatic field is conservative and does no net work over a closed path. Hence, electric potential can be associated with the electrostatic field but not the induced field. The following...
Generating Electromagnetic Radiations
The German physicist Heinrich Hertz (1857–1894) was the first to generate and detect certain types of electromagnetic waves in the laboratory. Starting in 1887, he performed a series of experiments that confirmed the existence of electromagnetic waves and verified that they travel at the speed of light. Hertz used an alternating-current RLC (resistor-inductor-capacitor) circuit that resonated at a known frequency and connected it to a loop of wire. High voltages induced across the gap in the...
Insulation Coordination
Insulation coordination is the process of matching electric equipment's insulation strength with protective device characteristics to protect the equipment against expected overvoltages. This selection is based on engineering judgment and cost. Equipment can generally withstand short-duration high transient overvoltages, but repeated tests with identical waveforms can yield inconsistent results. As a result, standard impulse voltage waveforms are used for testing, defined by specific times for...

