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Pulmonary Embolism III: Nursing Management
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ING2 PHD 域将基因组 H3 lysine 4 甲基化与活性基因抑制联系起来

Xiaobing Shi1, Tao Hong, Kay L Walter

  • 1Department of Biological Sciences, Stanford University, Stanford, California 94305, USA.

Nature
|May 27, 2006
PubMed
概括

三甲基化组织素H3 lysine 4 (H3K4me3) 可以积极抑制基因表达. ING2蛋白与H3K4me3结合,稳定了基因促进器的抑制复合体,影响了DNA损伤反应和瘤抑制.

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