社区对的控制:基于使用甲奶油的模型
D Taplin1, S L Porcelain, T L Meinking
1Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Florida.
Lancet (London, England)
|April 27, 1991
概括
巴拿马群岛的病爆发被有效地控制了使用百甲5%的奶油,证明了其在旧治疗失败的情况下的有效性. 持续控制需要持续的监测和治疗,以保持低发病率.
科学领域:
- 流行病学 流行病学
- 皮肤病学 皮肤病学
- 热带医学 热带医学
背景情况:
- 在巴拿马的库纳印第安人中,疹疫情持续了18年,尽管使用了林丹和克罗塔米顿治疗.
- 以前的治疗方法未能控制圣布拉斯群岛的疫情.
研究的目的:
- 为了评估甲5%奶油在控制疫情中的有效性.
- 评估治疗对的流行率和二次细菌感染的长期影响.
主要方法:
- 在一个拥有756名居民的岛屿上实施了一项使用百甲5%奶油的全社区治疗计划.
- 在干预之前,干预期间和干预后对的流行情况进行了监测,包括治疗中断和失去控制的时期.
- 还对细菌性皮肤感染进行了监测.
主要成果:
- 在大量使用甲酸5%奶油治疗后,疹患病率从33%降至1%以下.
- 持续的低患病率 (<1.5%) 在持续的监测和治疗下维持了超过3年.
- 在3周的药物供应中断期间,患病率增加到3.6%,控制失去了后,患病率增加到12%.
- 细菌性皮肤感染在控制后显著减少.
结论:
- 五分之一的甲基是一种安全且高效的治疗,即使在对林丹耐药的地区也是如此.
- 持续监测和及时治疗对于维持长期控制至关重要.
- 有效的管理可以导致二次细菌性皮肤感染的减少.
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