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Updated: Aug 3, 2026

On-chip Isotachophoresis for Separation of Ions and Purification of Nucleic Acids
10:32

On-chip Isotachophoresis for Separation of Ions and Purification of Nucleic Acids

Published on: March 2, 2012

通过相关的纯核酸酸酶进行过渡状态的模拟区分

Erika A Taylor Ringia1, Peter C Tyler, Gary B Evans

  • 1Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

Journal of the American Chemical Society
|June 1, 2006
PubMed
概括

过渡状态的类似物Immucillins和DADMe-Immucillins是针对纯核酸酸酶 (PNP) 酶而设计的. 模仿过渡状态几何学成功地区分了结合亲和力,尽管在人类和牛PNP中保留了活性位点.

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