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Updated: Jun 26, 2026

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
14:44

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

Published on: December 16, 2013

蛋白质-连接体NOE匹配:一种高通量方法用于结合姿势评估,不需要蛋白质NMR共振赋值

Keith L Constantine1, Malcolm E Davis, William J Metzler

  • 1Bristol Myers Squibb Pharmaceutical Research Institute, P.O. Box 4000, Princeton, New Jersey 08543, USA. keith.constantine@bms.com

Journal of the American Chemical Society
|June 1, 2006
PubMed
概括

这项研究引入了一种新的方法,可以使用核Overhauser效应 (NOE) 数据来确定蛋白质-连接体结合姿势,而不需要蛋白质NMR赋值. 这种方法简化了结构生物学,仅依赖于连接体NMR赋值.

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