在 dobutamine 输注期间对冠状动脉疾病的心声检测
S G Sawada1, D S Segar, T Ryan
1Department of Medicine, Indiana University School of Medicine, Indianapolis.
Circulation
|May 1, 1991
概括
多布胺应激回声心电图是检测冠状动脉疾病 (CAD) 的安全和准确方法. 这种诊断工具可以有效地识别显著的CAD并预测其程度,即使在患有异常静止心电回声图的患者中也是如此.
科学领域:
- 心脏病学 心脏病学
- 诊断成像 诊断成像 诊断成像
- 无创性心脏检测 无创性心脏检测
背景情况:
- 在dobutamine输注期间的二维回声心电图是检测冠状动脉疾病 (CAD) 的一种拟议方法.
- 多布胺应激心声扫描 (DSE) 对于CAD检测的安全性和诊断价值仍需确定.
研究的目的:
- 评估 dobutamine 应激回声心力学检测冠状动脉疾病的安全性和诊断准确性.
- 评估DSE预测CAD程度的能力,特别是在基线壁运动异常的患者中.
主要方法:
- 103名患者接受了DSE,分步输注多布他胺,最高达30微克/千克/分钟.
- 心声图被数字存储,以便同时分析休息和压力图像.
- 新区域壁运动异常的发展作为终点;用于比较的定量冠状动脉血管学.
主要成果:
- 在检测显著的冠状动脉疾病 (≥50%狭窄) 方面,DSE表现出高灵敏度 (89%) 和特异性 (85%).
- 对于单血管疾病,敏感度为81%,对于多血管或左主疾病,敏感度为100%.
- 没有出现症状性心律失常或因缺血引起的并发症,这表明安全性概况良好.
结论:
- 多布胺应激回声心电图是诊断冠状动脉疾病的安全和准确的非侵入性方法.
- DSE有效地预测了CAD的程度,特别是在静止心电图上预先存在区域壁运动异常的患者中.
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