重新思考微处理器的想法
Hervé Seitz1, Phillip D Zamore
1Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01532, USA.
Cell
|June 6, 2006
概括
微RNAs (miRNAs) 是从初级转录处理的基因表达调节剂. 这些转录的结构特征确保了Drosha-DGCR8酶复合物的精确处理,以产生功能性miRNA.
科学领域:
- 分子生物学分子生物学
- 遗传学 是一个遗传学.
- 生物化学 生物化学
背景情况:
- 微RNA (miRNA) 是小型非编码RNA分子,在转录后基因调节中起着至关重要的作用.
- miRNAs从较长的初级miRNA (pri-miRNA) 转录中通过一系列涉及特定酶的步骤进行处理.
- 了解控制精确miRNA生物发生的机制对于理解基因表达控制至关重要.
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