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Updated: May 2, 2026

Retroviral Infection of Murine Embryonic Stem Cell Derived Embryoid Body Cells for Analysis of Hematopoietic Differentiation
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血液形成是由TGFbeta通路的TIF1gamma和Smad4分支控制的

Wei He1, David C Dorn, Hediye Erdjument-Bromage

  • 1Cancer Biology and Genetics Program and Howard Hughes Medical Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

Cell
|June 6, 2006
PubMed
概括

转录介质因子1gamma (TIF1gamma) 与Smad4竞争,以结合Smad2/3,影响细胞命运. 这种相互作用产生了不同的Smad2/3-TIF1gamma和Smad2/3-Smad4通路,以响应TGFbeta信号.

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