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低出生体重和早产,苏格兰,1981-84:父母职业的影响
Lancet (London, England)
|August 17, 1991
概括
父母的职业可能会影响早产和低出生体重,特别是在特定行业的母亲暴露. 然而,对早产的总体职业影响似乎有限,母亲因素比父亲因素更为重要.
科学领域:
- 职业健康 职业健康 职业健康
- 生殖流行病学 生殖流行病学
- 围产期研究 围产期研究
背景情况:
- 父母的职业是不良妊娠结果的潜在决定因素.
- 以前的研究表明,某些职业与婴儿健康之间存在联系,但证据不一致.
- 了解职业风险对于针对产前护理的公共卫生干预至关重要.
研究的目的:
- 调查父母职业与早产和低出生体重风险之间的关联.
- 确定可能对胎儿发育构成风险的特定职业暴露.
- 为了区分母亲与父亲职业暴露的影响.
主要方法:
- 在苏格兰 (1981-1984) 接受252,147名活产婴儿的全国性研究.
- 收集关于母亲/父亲职业,出生体重和妊娠年龄的数据.
- 统计分析控制了诸如孕产妇年龄,怀孕和社会阶级等混因素.
主要成果:
- 在父母从事手工职业的孩子中,早产和低出生体重更为常见.
- 母亲使用电器,金属或皮革制品的工作增加了50%以上的早产/低出生体重风险.
- 父亲的职业表现出有限的关联,除了陶工人有早产风险增加;对于怀孕年龄的小风险在很大程度上不受职业的影响.
结论:
- 父母的职业暴露似乎不会对早产风险产生重大影响.
- 当出现不良影响时,与母亲的职业暴露更强烈相关.
- 进一步研究特定的母亲职业危险是有必要的,以告知保护措施.
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