相关实验视频
Updated: Jul 14, 2026

05:26
A Venturi Effect Can Help Cure Our Trees
Published on: October 1, 2013
树作为释放氧化的支架
Nathan A Stasko1, Mark H Schoenfisch
1Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
Journal of the American Chemical Society
|June 22, 2006
概括
研究人员开发了释放氧化 (NO) 的新型树脂合物. 这些树枝状体表现出增强的NO储存能力和持续释放,提供了改进的NO输送系统.
科学领域:
- 聚合物化学 聚合物化学
- 材料科学 材料科学 材料科学
- 纳米技术 纳米技术
背景情况:
- 氧化 (NO) 是具有治疗潜力的关键信号分子.
- 由于NO的不稳定性,开发有效的NO输送系统具有挑战性.
- 登德里默为药物输送应用提供了多功能支架.
研究的目的:
- 为了合成和表征释放氧化 (NO) 的树状分子合物.
- 评估这些新材料的NO储存能力和释放动力学.
- 探索树枝状体作为先进的NO存储和输送系统的潜力.
主要方法:
- 修改了第3代和第5代聚烯胺树突 (DAB-Am-16和DAB-Am-64) 的氨基功能.
- 在高压下 (5 atm) 使用N-diazeniumdiolate捐赠体将NO加载到树状体支架上.
- 在生理条件下 (pH 7.4,37°C) 的NO储存容量和体外释放动力学的表征.
主要成果:
- 二次氨基树突结合物显示出高NO储存能力 (高达5.6微摩尔NO/mg).
- NO的释放是质子启动的,在生理条件下自发发生.
- 观察到持续的NO释放 (>16小时),比小分子对应物长得多,表明树突效应.
结论:
- 聚烯胺树状体可以有效地功能化,以创建强大的NO释放合物.
- 这些树突结合物代表了宏分子NO捐赠者的显著进步,提供了卓越的储存和持续释放.
- 树突体的多价性性质允许开发多功能平台,用于各种NO输送应用.
相关概念视频
Redox Reactions
Oxidation-reduction or redox reactions involve the transfer of electrons from one molecule or atom to another. When an atom gains an electron, another atom must lose an electron, meaning oxidation and reduction must occur together. Since the redox occurs in pairs, the atom that gets oxidized is also called the reducing agent or reductant, and the atom that is reduced is also called the oxidizing agent or oxidant. A straightforward way to remember the definitions of oxidation and reduction is...
What is Photosynthesis?
Photosynthesis is a multipart, biochemical process that occurs in plants as well as in some bacteria. It captures carbon dioxide and solar energy to produce glucose. Glucose stores chemical energy in the form of carbohydrates. The overall biochemical formula of photosynthesis is 6 CO2 + 6 H2O + Light energy → C6H12O6 + 6 O2. Photosynthesis releases oxygen into the atmosphere and is largely responsible for maintaining the Earth’s atmospheric oxygen content.
The Calvin Cycle
OverviewOxygenic photosynthesis plays a central role in the global carbon and oxygen cycles. The carbohydrates produced support nearly all food webs, while the oxygen by‑product enables aerobic life.Light‑dependent and light‑independent reactionsPhotosynthesis occurs in two main stages, each in a different part of the chloroplast: light‑dependent reactions and light‑independent reactions, also called the Calvin‑Benson cycle or simply the Calvin cycle.Light‑dependent reactions take place in the...
What is Photosynthesis?
All living organisms on Earth are directly or indirectly dependent on photosynthesis. It is the only biological process that can capture energy from sunlight and convert it into chemical energy that every organism can use to power its metabolism. Photosynthesis is also the source of oxygen required by many living organisms.
Types of Organisms Based on their Modes of Nutrition
Broadly, there are two main categories of organisms based on their modes of nutrition — autotrophs and heterotrophs. An...
Types of Organisms Based on their Modes of Nutrition
Broadly, there are two main categories of organisms based on their modes of nutrition — autotrophs and heterotrophs. An...
Oxygenic Photosynthesis
Oxygenic photosynthesis is a fundamental process in which light energy is harnessed to drive the oxidation of water, leading to the production of molecular oxygen (O₂), adenosine triphosphate (ATP), and nicotinamide adenine dinucleotide phosphate (NADPH). This process is essential for sustaining aerobic life on Earth and is primarily carried out by cyanobacteria, algae, and plants. The core of oxygenic photosynthesis lies in the thylakoid membranes, where chlorophyll pigments facilitate light...
Carbon-dioxide Fixation
Carbon dioxide fixation in prokaryotes enables the assimilation of inorganic carbon into organic molecules, supporting biosynthetic pathways, sustaining ecosystems, and contributing to the global carbon cycle. It also has industrial applications in carbon capture and bioproduct synthesis. Autotrophic organisms rely on this process to utilize CO₂ as a carbon source in diverse environments.The Calvin CycleThe Calvin cycle is the most widespread carbon fixation mechanism, primarily used by...

