隐形眼镜和其他微生物角质炎的危险因素
J K Dart1, F Stapleton, D Minassian
1Department of Clinical Ophthalmology, Moorfields Eye Hospital, London, UK.
Lancet (London, England)
|September 14, 1991
概括
隐形眼镜的佩戴显著增加了微生物角膜炎的风险,这是一个严重的眼睛感染. 与其他镜头类型相比,软隐形眼镜的长时间磨损构成最高的风险.
科学领域:
- 眼科医生 眼科 眼科
- 微生物学 微生物学
- 流行病学 流行病学
背景情况:
- 微生物角膜炎是一种罕见但严重的眼睛疾病,主要与隐形眼镜 (CL) 使用有关.
- 了解与CL磨损和其他原因相关的特定风险对于预防至关重要.
研究的目的:
- 评估隐形眼镜磨损的相对风险和其他导致微生物角膜炎的因素.
- 量化与CL使用相关的微生物角质炎的可归因风险.
主要方法:
- 进行了一项病例控制研究,涉及91例角膜炎病例,其中60例是隐形眼镜使用者.
- 相对风险 (RR) 和人口可归因风险百分比 (PAR%) 为各种原因和CL类型计算.
主要成果:
- 与没有预先条件的病例相比,佩戴隐形眼镜具有较高的角膜炎相对风险 (RR=80).
- 隐形眼镜的佩戴占了65%的人口可归因于微生物角质炎的风险.
- 长时间佩戴软隐形眼镜的风险明显高 (RR=21) 比每天佩戴软隐形眼镜 (RR=3.6) 或硬隐形眼镜 (RR=1.3) 高得多.
结论:
- 隐形眼镜的磨损是微生物角膜炎的首要原因,特别是软长时间佩戴的镜头.
- 连续佩戴隐形眼镜超过六天会增加患这种危及视力的疾病的风险.
相关概念视频
Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Focusing of Light in the Eye
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
Photoreceptors and Visual Pathways
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Microbiome of the Eye
The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...


