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相关概念视频

Oogenesis02:07

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
Oogenesis01:22

Oogenesis

Oogenesis,  the process of developing egg cells (female gametes), occurs within the ovaries and is fundamental to female fertility. This sequence begins during fetal development when diploid oogonia in the developing ovaries undergo mitotic divisions to produce primary oocytes. By birth, these primary oocytes enter prophase I of meiosis but become arrested in this stage, remaining suspended until puberty.
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is known...

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相关实验视频

Updated: Jul 11, 2026

Retrieval of Mouse Oocytes
08:42

Retrieval of Mouse Oocytes

Published on: April 28, 2007

成年小鼠的排卵卵细胞来自于非循环的生殖细胞.

Kevin Eggan1, Sara Jurga, Roger Gosden

  • 1The Stowers Medical Institute, Harvard Stem Cell Institute and The Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

Nature
|June 27, 2006
PubMed
概括

骨髓细胞在雌性哺乳动物中不会产生排卵的卵细胞. 这项研究没有发现循环的骨髓细胞有助于卵细胞的产生或女性生育能力的证据.

科学领域:

  • 生殖生物学 生殖生物学
  • 细胞生物学 细胞生物学
  • 血液学 血液学 血液学

背景情况:

  • 传统上,人们认为雌性哺乳动物在出生前就有了有限的卵细胞供应.
  • 最近的研究表明,循环的骨髓细胞可能会持续补充卵巢卵细胞池.

研究的目的:

  • 研究循环细胞对女性生育能力的生理相关性.
  • 为了确定骨髓衍生细胞能否在雌性哺乳动物中产生成熟卵细胞.

主要方法:

  • 使用了移植和生物小鼠模型.
  • 在正常和受损条件下评估循环骨髓细胞在正常和受损条件下形成排卵卵细胞的能力.

主要成果:

  • 没有证据表明骨髓细胞有助于形成成熟的,排卵的卵细胞.
  • 在卵巢中观察到的循环细胞显示出血白细胞的特征,而不是生殖细胞.

结论:

  • 在雌性哺乳动物中,循环的骨髓细胞不会促进排卵卵细胞的产生.
  • 产后卵巢似乎没有被来自骨髓的循环生殖细胞补充.

更多相关视频

Differentiation of Newborn Mouse Skin Derived Stem Cells into Germ-like Cells In vitro
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Differentiation of Newborn Mouse Skin Derived Stem Cells into Germ-like Cells In vitro

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Whole Ovary Immunofluorescence, Clearing, and Multiphoton Microscopy for Quantitative 3D Analysis of the Developing Ovarian Reserve in Mouse
12:36

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Last Updated: Jul 11, 2026

Retrieval of Mouse Oocytes
08:42

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Published on: April 28, 2007

Differentiation of Newborn Mouse Skin Derived Stem Cells into Germ-like Cells In vitro
09:47

Differentiation of Newborn Mouse Skin Derived Stem Cells into Germ-like Cells In vitro

Published on: July 16, 2013

Whole Ovary Immunofluorescence, Clearing, and Multiphoton Microscopy for Quantitative 3D Analysis of the Developing Ovarian Reserve in Mouse
12:36

Whole Ovary Immunofluorescence, Clearing, and Multiphoton Microscopy for Quantitative 3D Analysis of the Developing Ovarian Reserve in Mouse

Published on: September 3, 2021