认知行为疗法与佐皮克隆用于老年人慢性初级失眠的治疗:一个随机对照试验
Børge Sivertsen1, Siri Omvik, Ståle Pallesen
1Department of Clinical Psychology, University of Bergen, Bergen, Norway. borge.sivertsen@psykp.uib.no
JAMA
|June 29, 2006
概括
与佐皮克隆相比,认知行为疗法 (CBT) 显著改善了慢性失眠的老年人睡眠效率,并减少了夜间醒来. 在这一群体中,CBT为失眠提供了优质的短期和长期管理.
科学领域:
- 老年学是一门学科.
- 睡眠医学 睡眠医学
- 临床心理学 临床心理学
背景情况:
- 失眠在老年人中很普遍,导致不良的健康和社会结果.
- 现有治疗方法在盲目,安慰剂对照试验中缺乏直接比较.
- 慢性原发性失眠会影响到老年人口的很大一部分.
研究的目的:
- 为了比较认知行为疗法 (CBT) 与老年人慢性初级失眠的药物治疗的短期和长期有效性.
- 用客观和主观睡眠测量来评估临床疗效.
主要方法:
- 这是一项随机,双盲,安慰剂对照试验,涉及46名患有慢性原发性失眠的成年人 (平均年龄为60.8岁).
- 干预措施包括CBT (n=18),佐皮克隆 (n=16) 或安慰剂 (n=12) 持续6周,并对活性治疗进行6个月的随访.
- 睡眠效率,总觉醒时间,总睡眠时间和慢波睡眠通过多睡眠学和睡眠日记进行了评估.
主要成果:
- 认知行为疗法 (CBT) 在四个措施中的三个方面表现出优异的短期和长期结果,与佐皮克隆相比.
- 在大多数结局中,佐皮克隆与安慰剂没有显著差异.
- 与佐皮克隆和安慰剂相比,CBT显著提高了睡眠效率 (81.4%至90.1%),并增加了慢波睡眠.
结论:
- 认知行为疗法 (CBT) 干预措施在老年人失眠的短期和长期管理方面比佐皮克隆更有效.
- CBT导致睡眠质量和建筑的持续改善.
- 研究结果支持CBT作为老年人慢性失眠的主要治疗方法.
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