抑郁症和心血管疾病:治愈心碎的人
1Veterans Affairs Medical Center and University of California, San Francisco Medical Center, San Francisco, CA 94121, USA. mary.whooley@ucsf.edu
JAMA
|June 29, 2006
概括
重度抑郁症显著增加心脏病和心血管不良结果的风险. 在心血管患者中识别和治疗抑郁症至关重要,尽管它对结果的影响需要进一步研究.
科学领域:
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
- 临床医学 临床医学
背景情况:
- 重度抑郁症 (MDD) 是一种已知的冠心病 (CHD) 发展的风险因素,并且在患有心血管疾病 (CVD) 的患者中恶化了结果.
- 抑郁症影响了相当一部分心血管患者,20%的心血管疾病门诊患者和33%的充血性心力衰竭患者患有抑郁症.
- 在心血管病患者群体中,抑郁症的识别和治疗存在重大差距.
研究的目的:
- 评估患有心血管疾病 (CVD) 的个体中严重抑郁症的意义.
- 为心血管患者群体中抑郁症的识别和管理提供实用策略.
主要方法:
- 审查现有的关于主要抑郁症和心血管疾病之间的关系的文献.
- 在门诊心血管环境中分析抑郁症的患病率.
- 对选择性血清素再吸收抑制剂 (SSRI) 用于治疗心血管疾病患者抑郁症的安全性和疗效的评估.
主要成果:
- 重度抑郁症是新的心血管事件和已确诊心脏病患者的较差结果的已知的风险因素.
- 抗抑郁药治疗,特别是SSRI,对于心血管患者来说通常是安全的.
- 证实了SSRI在减少抑郁症状和提高生活质量的有效性.
结论:
- 重度抑郁症是患有心血管疾病的患者的关键性,经常被忽视的并发症.
- 虽然抑郁症治疗对心血管结果的直接影响需要进一步调查,但SSRI提供了一种安全有效的手段来管理抑郁症并改善患者的福祉.
- 需要临床指导,以系统地查和治疗心血管保健机构的抑郁症.
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