一个功能直角的连接体-受体对,通过准甲状腺激素受体的全性机制来创建

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Updated: Aug 3, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
07:01

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

Published on: April 17, 2013

A Quamrul Hassan1, John T Koh

  • 1Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA.

Journal of the American Chemical Society
|July 6, 2006
PubMed
概括

一种新型的合成激素类似物,QH2,可以选择性地激活突变的甲状腺激素受体 (TRbeta H435A),而不会影响野生型受体. 这一发现为使用核受体进行精确基因调节提供了新的可能性.

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