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升的内甲素-1水平会通过PKC依赖的途径损害氧化的稳态

Danny Ramzy1, Vivek Rao, Laura C Tumiati

  • 1Heart Transplant Program, University of Toronto, Toronto, Ontario, Canada.

Circulation
|July 6, 2006
PubMed
概括

升高的内甲素-1 (ET-1) 通过通过蛋白激酶C (PKC) 信号来抑制内皮内甲氧化合成酶 (eNOS) 表达,从而损害氧化 (NO) 生产. ET-1 抗可能改善血管平衡.

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