低梯度大动脉狭窄的门置换后的长期结果:假肢患者不匹配的影响
Alexander Kulik1, Ian G Burwash, Varun Kapila
1Division of Cardiac Surgery, University of Ottawa, Ottawa, Ontario, Canada.
Circulation
|July 6, 2006
概括
患有低梯度大动脉狭窄症 (LGAS) 的患者在大动脉置换 (AVR) 后经历了更糟糕的结果. 假肢-患者不匹配 (PPM) 进一步加剧了这些结果,强调需要避免在LGAS患者.
科学领域:
- 心脏病学 心脏病学
- 心脏外科手术 心脏外科手术
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 大动脉置换 (AVR) 后低梯度大动脉狭窄 (LGAS) 的长期结果尚未得到充分确立.
- 假肢-患者不匹配 (PPM) 可能会影响接受AVR的LGAS患者的结果.
研究的目的:
- 为了确定LGAS患者在AVR后的长期结果.
- 评估PPM在AVR后对LGAS患者的影响.
主要方法:
- 自1990年以来,对664名因大动脉狭窄而接受AVR的患者进行了前性随访.
- 根据特定的门面积,梯度和LV喷射分数标准定义的LGAS.
- 多变量回归分析以确定存活率,无CHF,和LV质量回归.
主要成果:
- 与非LGAS患者相比,LGAS患者的10年生存率 (72.7%) 和无CHF (68.2%) 显著降低.
- 在LGAS患者中,PPM与CHF发病率增加,LV质量回归受损以及死亡率上升的趋势有关.
- 在AVR之后,LGAS患者的结果明显恶化.
结论:
- 与没有LGAS的患者相比,LGAS患者在AVR后的长期结果较差.
- PPM对LGAS患者的长期结果产生负面影响,应该预防.
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