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一个电气刺激的新门关节的发展
N S Williams1, J Patel, B D George
1Surgical Unit, Royal London Hospital, Whitechapel, UK.
Lancet (London, England)
|November 9, 1991
概括
这项研究通过修改gracilis肌肉转移和电刺激来改善便失禁的外科手术技术,成功地恢复了患者的失禁,并为永久性口腔提供了替代方案.
科学领域:
- 手术方面的创新.
- 重建性手术是一种重建性手术.
- 生物医学工程 生物医学工程
背景情况:
- 使用转移的gracilis肌肉手术创建一个新关节已经面临由于肌肉疲劳的挑战.
- 之前试图将肌肉转换为耐疲劳型的尝试产生了不一致的结果.
研究的目的:
- 描述使用电刺激转移的Gracilis肌肉对新关节技术的修改.
- 改善便失禁患者的长期功能结果.
主要方法:
- 转移的Gracilis肌肉与一个完全植入的刺激器,以转换快速抽肌肉慢抽肌肉.
- 包括血管延迟,直接的神经刺激和间歇性高频刺激.
- 适用于20名关节缺陷患者和12名缺失/切割的患者.
主要成果:
- 修改后的技术,包括2-4个特定的修改,导致相比以前的方法 (0-1个修改) 的故障显著减少.
- 在患有严重便失禁的患者中恢复了 incontinence.
结论:
- 增强的新关节技术为便失禁提供了可行的解决方案,可能避免需要永久性口腔.
- 进一步的修改显著提高了肌肉转移用于关节重建的成功率.
相关概念视频
Action Potentials
Overview
Synaptic Signaling
Neurons communicate at synapses, or junctions, to excite or inhibit the activity of other neurons or target cells, such as muscles. Synapses may be chemical or electrical.
Most synapses are chemical, meaning an electrical impulse or action potential spurs the release of chemical messengers called neurotransmitters. The neuron sending the signal is called the presynaptic neuron, and the neuron receiving the signal is the postsynaptic neuron.
The presynaptic neuron fires an action potential that...
Most synapses are chemical, meaning an electrical impulse or action potential spurs the release of chemical messengers called neurotransmitters. The neuron sending the signal is called the presynaptic neuron, and the neuron receiving the signal is the postsynaptic neuron.
The presynaptic neuron fires an action potential that...
Action Potential
Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
Electrical Synapses
Electrical synapses found in all nervous systems play important and unique roles. In these synapses, the presynaptic and postsynaptic membranes are very close together (3.5 nm) and are actually physically connected by channel proteins forming gap junctions.
Gap junctions allow the current to pass directly from one cell to the next. In contrast, in the chemical synapse, the neurotransmitters carry the information through the synaptic cleft from one neuron to the next. They consist of two...
Gap junctions allow the current to pass directly from one cell to the next. In contrast, in the chemical synapse, the neurotransmitters carry the information through the synaptic cleft from one neuron to the next. They consist of two...
Action Potential
Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
Neuronal Communication
Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...

