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Murine Renal Transplantation Procedure
Published on: July 10, 2009
在异常下泌尿道中移植脏
H S Cairns1, B Leaker, C R Woodhouse
1Institute of Urology and Nephrology, University College London, UK.
Lancet (London, England)
|November 30, 1991
概括
对于下尿路异常的患者来说,脏移植是安全有效的,显示出与其他脏移植接受者相似的移植存活率. 膀功能的术前评估对于成功的结果至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 移植医学 移植医学
背景情况:
- 对于初级泌尿器官异常患者的移植的安全性和疗效仍然存在疑问.
- 之前的研究还没有为这个特定的患者队列确切地确定结果.
- 了解移植的存活率和长期功能对于患者管理至关重要.
研究的目的:
- 评估移植在患有下尿路异常的患者中的安全性和有效性.
- 为了比较这个群体中的移植存活率和功能,与非泌尿末期功能衰竭的接受者.
- 确定影响移植患者下泌尿道异常结果的因素.
主要方法:
- 在1977年至1989年间对62名患有各种下尿路异常的患者进行的69次脏移植的回顾性分析.
- 移植存活率与150名全移植接受者 (157个移植) 进行了对比,这些接受者患有末期功能衰竭的非泌尿病原因.
- 在分析中包括患有尿路转移 (乳腺管道,直肠膀) 的患者.
主要成果:
- 泌尿器科组的移植存活率与非泌尿器科对照组相比较.
- 没有一个特定的泌尿学子组显示了显著较差的移植存活率.
- 患有复发性尿路感染和有外流阻塞病史的患者显示,移植功能恶化的趋势.
结论:
- 脏移植是患有下泌尿道异常的患者的安全有效的治疗选择.
- 患有阴道管的患者表现出相似的移植存活率和功能,并发症很少.
- 膀排空和尿动力学的术前评估对于优化这些患者的治疗结果至关重要.
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