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在接受静脉输血栓溶解的中风患者中早期复发性缺血性中风
Dimitrios Georgiadis1, Stefan Engelter, Barbara Tettenborn
1Department of Neurology, University of Zürich, Frauenklinikstrasse 26, 8091 Zürich, Switzerland. Dimitrios.Georgiadis@usz.ch
Circulation
|July 13, 2006
概括
在接受静脉输血栓溶解的患者中,早期复发性缺血性中风是罕见的,发生在不到1%的病例中. 症状性内出血更为常见,治疗后的时间不同.
科学领域:
- 神经学 神经学
- 心血管医学 心血管医学
- 紧急医疗 紧急医疗
背景情况:
- 评估早期复发性缺血性中风发生率在接受静脉内组织类型等离子体激活剂 (tPA) 治疗的患者中.
- 将复发性缺血性中风的时间模式与症状性内出血 (ICH) 进行比较.
研究的目的:
- 为了确定tPA治疗后早期复发性缺血性中风的频率.
- 在急性中风患者中,比较复发性缺血性中风和症状性ICH的时间.
主要方法:
- 对341名急性中风患者的前性收集的基于人口的数据进行了回顾性分析,这些患者接受了tPA.
- 主要结局:24小时内神经系统恶化 (NIH中风量表≥4分),归因于复发性缺血性中风或症状性ICH.
- 在2001年1月至2004年11月期间,从8个瑞士医疗中心收集的数据.
主要成果:
- 早期复发性缺血性中风发生在0.59%的患者中 (2/341).
- 有症状的ICH发生在4.40%的患者中 (15/341).
- 血栓溶解期间发生了复发性缺血性中风;输注后2-22小时发生了症状性ICH.
结论:
- 复发性缺血性中风是接受静脉血栓溶解的急性中风患者早期神经系统恶化的不常见原因.
- 复发性缺血性中风的时间发生与症状性缺血性中风的时间发生有显著差异.
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