用防晒预防紫外线引起的唇部疹
J F Rooney1, Y Bryson, M L Mannix
1Laboratory of Oral Medicine, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20892.
Lancet (London, England)
|December 7, 1991
概括
暴露在阳光下可能会引发反复出现的唇疹. 在暴露于紫外线 (UV) 光线之前涂抹防晒,在临床试验中有效防止了感冒的重新激活.
科学领域:
- 皮肤病学 皮肤病学
- 病毒学 病毒学
- 照相医疗 (photomedicine) 是一种医学.
背景情况:
- 复发的唇疹 (感冒疹) 往往是阳光照射之前的.
- 紫外线 (UV) B辐射是已知的疹简单病毒 (HSV) 再激活的触发因素.
研究的目的:
- 评估防晒剂在防止紫外线辐射诱导的复发性唇的重新激活方面的有效性.
- 评估防晒在控制阳光触发的感冒病爆发中的作用.
主要方法:
- 进行了一项双盲,安慰剂控制的交叉试验.
- 38名有复发性唇疹病史的患者在两次接触紫外线.
- 在紫外线暴露之前,涂抹防晒或安慰剂在嘴唇上.
主要成果:
- 在接受安慰剂和紫外线照射后,71%的患者出现唇部疹 (平均复发时间:2.9天).
- 在紫外线暴露之前涂抹防晒时,没有出现感冒病变.
- 只有一个患者在使用防晒后在暴露部位脱落了HSV.
结论:
- 紫外线光是一种强大的激发器,可以激活口唇疹.
- 局部防晒的应用在预防阳光引起的反复性唇疹感染方面似乎是有效的.
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