在接受脏替代疗法的残疾患者中膀瘤
M Yaqoob1, P McClelland, G M Bell
1Royal Liverpool University Hospital, UK.
Lancet (London, England)
|December 21, 1991
概括
接受透析的神经性膀患者面临尿道膀瘤的高风险. 建议在移植之前定期进行泌尿学查和潜在的囊切除术,以减轻这种风险.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
背景情况:
- 末期病 (ESRD) 在患有神经性膀的患者中,通常是由于分脊椎或脊髓损伤,需要定期进行血液透析.
- 这些患者也可能接受移植.
- 在这种特定人群中,尿瘤的风险尚未得到充分确立.
研究的目的:
- 研究成年患者尿膀瘤的发病率ESRD二次性的神经性膀接受血液透析.
- 评估在接受脏移植的患者中这些瘤的发生情况.
主要方法:
- 随访了一组由14名成年患者组成的队列,他们因神经性膀而患有ESRD.
- 患者接受定期血液透析,平均持续时间为20个月.
- 七名患者接受了脏移植;尿道状况受到监测.
主要成果:
- 在14名患者中,有4名患者 (28.6%) 患有泌尿膀瘤.
- 在透析患者中发生了三例状细胞癌.
- 一个差异化过渡细胞癌被诊断在一个移植后的病人.
- 这四名患者都患有广泛的转移性疾病,并在诊断后8周内死亡.
结论:
- 在透析中患有神经性膀的患者有很大的风险发展尿膀瘤.
- 对这些患者来说,即使在开始透析后,定期进行泌尿学评估也至关重要.
- 在移植之前的预防性全囊切除术可能会降低这些罕见但具有攻击性的瘤的风险.
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