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相关概念视频

Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

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Updated: Jul 16, 2026

Facial Transplants in Xenopus laevis Embryos
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Facial Transplants in Xenopus laevis Embryos

Published on: March 26, 2014

第一个人脸整体移植:早期报告

Bernard Devauchelle1, Lionel Badet, Benoit Lengelé

  • 1Departement of Maxillofacial Surgery, Centre Hospitalier Universitaire Amiens, France. devauchelle.bernard@chu-amiens.fr

Lancet (London, England)
|July 18, 2006
PubMed
概括

面部复合组织移植是面部严重缺陷的可行选择,提供良好的美容和功能结果. 这种案例研究表明,成功重建具有出色的外观,感觉和患者接受.

科学领域:

  • 重建性手术是一种重建性手术.
  • 移植免疫学 移植免疫学
  • 面部解剖学 面部解剖学

背景情况:

  • 扩展的软组织面部缺陷带来了重大的重建挑战.
  • 自主组织移植往往会导致低于最佳的美容和功能结果.
  • 复合组织移植被探索为面部重建的有价值的替代方案.

研究的目的:

  • 评估复合面部组织移植对广泛缺陷的可行性和结果.
  • 评估面部整体移植后的美容,功能和感官恢复.
  • 研究面部移植中免疫抑制和排斥的管理.

主要方法:

  • 一名38岁的患者从脑死亡的捐赠者那里接受了复合面部全移植 (中部和下部面部).
  • 外科手术包括面部血管的再血管化,粘膜修复,神经解剖 (感觉和运动) 和皮肤关闭.
  • 免疫抑制包括胆红蛋白,塔克罗利斯,菌酸莫菲蒂尔,普雷迪尼松和捐赠者骨髓输液.
  • 手术后的随访包括例行检查,活检,物理治疗和心理支持.

主要成果:

  • 最初的术后过程没有任何事件,没有手术并发症.
  • 骨髓移植和免疫抑制被很好地容忍,轻微的排斥症状由普得尼松治疗.

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Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
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Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation
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Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation

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Last Updated: Jul 16, 2026

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Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
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Published on: March 1, 2015

Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation
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Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation

Published on: December 30, 2025

  • 观察到优秀的解剖和心理整合,以及恢复感觉.
  • 早期的功能恢复包括改善饮食和语言,并持续进行动态唇部运动的物理治疗.

    • 结论:

    • 四个月的结果证明了复合面部组织移植的可行性.
    • 该程序在外观,灵敏度和患者接受度方面取得了早期成功.
    • 长期的功能结果将被评估,但初步发现支持移植的成功.