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Updated: Jun 25, 2026

2D-HELS MS Seq: A General LC-MS-Based Method for Direct and de novo Sequencing of RNA Mixtures with Different Nucleotide Modifications
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新的RNA标记方法在2H NMR放松光谱中显著提高了灵敏度

Pramodh Vallurupalli1, Lincoln Scott, Mirko Hennig

  • 1Department of Medical Genetics, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario M5S1A8, Canada.

Journal of the American Chemical Society
|July 20, 2006
PubMed
概括

这项研究引入了一种新的RNA标记方法,用于精确测量分子动力学. 这种新技术提高了灵敏度,使得可以在各种时间尺度上详细研究RNA运动.

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