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Updated: Jul 13, 2026

Enrichment of Bruch's Membrane from Human Donor Eyes
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Published on: November 15, 2015

补充因子H多态性,补充激活剂,以及与年龄相关的黄斑变性风险

Dominiek D G Despriet1, Caroline C W Klaver, Jacqueline C M Witteman

  • 1Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands.

JAMA
|July 20, 2006
PubMed
概括

补充因子H (CFH) Y402H基因变异显著增加与年龄相关的黄斑变性 (AMD) 风险,特别是炎症. 这种遗传因素对AMD患病率有很大影响,特别是与吸烟或高C反应蛋白 (CRP) 相结合时.

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