在基因调节中模糊 cis 和 trans
Fabio Savarese1, Rudolf Grosschedl
1Max Planck Institute of Immunobiology, 79108 Freiburg, Germany.
Cell
|July 29, 2006
概括
一个单一的增强剂可以控制多个嗅觉受体 (OR) 基因,这解释了嗅觉感官神经元如何在1000多个中只选择一个基因. 这一发现揭示了嗅觉受体基因表达的复杂机制.
科学领域:
- 遗传学 是一个遗传学.
- 神经科学是一个神经科学.
- 分子生物学分子生物学
背景情况:
- 嗅觉感官神经元 (OSN) 表达了超过1000个嗅觉受体 (OR) 基因的广泛表达.
- 通过OSN实现单个OR基因单单基因表达的精确机制在嗅觉研究中仍然是一个关键问题.
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