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Updated: May 6, 2026

Assays for the Degradation of Misfolded Proteins in Cells
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Published on: August 28, 2016

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一个CK2-依赖的机制降解PML瘤抑制剂的降解

Pier Paolo Scaglioni1, Thomas M Yung, Lu Fan Cai

  • 1Cancer Biology and Genetics Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

Cell
|July 29, 2006
PubMed
概括

氨酸激酶2 (CK2) 促进了PML瘤抑制蛋白的降解. 抑制CK2恢复PML水平并增强其瘤抑制功能,为癌症提供潜在的治疗策略.

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