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Updated: Jul 10, 2026

Super-resolution Imaging of the Natural Killer Cell Immunological Synapse on a Glass-supported Planar Lipid Bilayer
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在纳米分辨率下成像细胞内光蛋白

Eric Betzig1, George H Patterson, Rachid Sougrat

  • 1Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, VA 20147, USA. betzige@janelia.hhmi.org

Science (New York, N.Y.)
|August 12, 2006
PubMed
概括

我们开发了光活性定位显微镜 (PALM) 用于细胞内蛋白质的高分辨率光学成像. 这种技术通过定位和组装来自可光激活光蛋白的数据来实现纳米分辨率.

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Published on: November 6, 2019

相关概念视频

Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been developed.