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在INTERHEART研究中,52个国家的烟草使用和心肌梗塞风险:一个病例控制研究
Koon K Teo1, Stephanie Ounpuu, Steven Hawken
1Population Health Research Institute, McMaster University-Hamilton Health Sciences, Hamilton, ON L8L 2X2, Canada.
Lancet (London, England)
|August 22, 2006
概括
烟草使用,包括吸烟和,显著增加急性心肌梗塞 (AMI) 的风险. 阻止所有形式的烟草,包括二手烟 (SHS),对于全球预防心血管疾病至关重要.
科学领域:
- 心血管流行病学心血管流行病学
- 烟草控制研究研究 烟草控制研究
- 公共卫生 公共卫生
背景情况:
- 全球范围内,吸烟是心血管疾病的主要可预防的原因.
- 评估各种烟草制品和二手烟暴露的全球风险至关重要.
研究的目的:
- 评估不同形式的烟草使用 (吸烟,无烟烟,二手烟) 与急性心肌梗塞 (AMI) 风险之间的关联.
主要方法:
- 一项标准化病例控制研究,涉及52个国家的27,089名参与者.
- 评估了与目前/以前吸烟,烟草类型,数量,无烟烟草和SHS暴露相关的风险.
- 控制吸烟者与非吸烟者之间的生活方式混因素.
主要成果:
- 当前吸烟显著增加了非致命性AMI风险 (OR2.95);风险随着香烟消费而增加.
- 前吸烟者甚至在戒烟20年后仍存在残留风险.
- 烟 (OR 2.23) 和SHS暴露 (OR 1.24-1.62) 也增加了AMI风险.
- 年轻男性的吸烟风险在人口中最高;SHS对从未吸烟的人来说是一个显著的风险.
结论:
- 烟草的使用,以各种形式,是AMI的主要全球原因之一,特别是在男性中.
- 阻止吸烟,烟和SHS暴露对于预防心血管疾病至关重要.
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