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巨细胞是调控T细胞耐受性的重要中间体

Li-Fan Lu1, Evan F Lind, David C Gondek

  • 1Department of Microbiology & Immunology, Dartmouth Medical School and the Norris Cotton Cancer Center, Lebanon, New Hampshire 03756, USA.

Nature
|August 22, 2006
PubMed
概括

巨细胞对于调节性T细胞依赖性免疫耐受性至关重要,与它们在过敏中的作用相反. 调节性T细胞通过IL-9激活巨细胞,调解区域性免疫抑制和全移植耐受性.

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