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通过组合性突变发生和选择揭示的EntB载体蛋白的局部蛋白相互作用表面

Jonathan R Lai1, Michael A Fischbach, David R Liu

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Journal of the American Chemical Society
|August 24, 2006
PubMed
概括

载体蛋白质是聚基合成酶 (PKS) 和非核糖体合成酶 (NRPS) 组合的关键. 在EntB-ArCP上局部的相互作用表面促进酸乙烯转移酶结合,与其他模块相互作用不同.

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