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Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
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通过跨主导RNA聚合酶突变阻断启动到延长的过渡

M Kashlev1, J Lee, K Zalenskaya

  • 1Institute of Molecular Genetics, U.S.S.R. Academy of Sciences, Moscow.

Science (New York, N.Y.)
|May 25, 1990
PubMed
概括

大肠杆菌RNA聚合酶中的突变通过防止DNA延长来破坏基因表达. 这种突变酶抑制细胞生长,并阻止野生型聚合酶进入促进体.

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