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Updated: Jul 15, 2026

Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study
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Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study

Published on: June 29, 2016

分享的人类T细胞受体Vβ使用到髓基蛋白的免疫主导区域

K W Wucherpfennig1, K Ota, N Endo

  • 1Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115.

Science (New York, N.Y.)
|May 25, 1990
PubMed
概括

研究人员在多发性硬化症 (MS) 患者中发现共享的T细胞受体 (TCR) Vβ基因使用,这些患者识别了髓基蛋白 (MBP). 这一发现可能会导致针对MS治疗的特定TCR结构的新免疫疗法.

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