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Updated: Jul 13, 2026

Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs
11:21

Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs

Published on: September 10, 2017

通过CTLA-4扭转TCR停止信号

Helga Schneider1, Jos Downey, Andrew Smith

  • 1Cell Signalling Section, Division of Immunology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK.

Science (New York, N.Y.)
|August 26, 2006
PubMed
概括

细胞毒性T淋巴细胞相关抗原4 (CTLA-4) 增强T细胞运动,减少T细胞受体信号传递. 这种机制降低了免疫细胞激活值,有可能预防自身免疫性疾病.

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