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Updated: Jul 13, 2026

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone
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Published on: February 23, 2017

需要阿尔戈纳特切片来实现异色沉默和扩散

Danielle V Irvine1, Mikel Zaratiegui, Niraj H Tolia

  • 1Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.

Science (New York, N.Y.)
|August 26, 2006
PubMed
概括

小干扰RNA (siRNA) 通过与RNA的基配对相互作用来引导基因组的修饰. 这一过程涉及Argonaute和RNA依赖RNA聚合酶复合体,用于异色沉默.

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¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)

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¹³C NMR: ¹H–¹³C Decoupling

The probability of having two carbon-13 atoms next to each other is negligible because of the low natural abundance of carbon-13. Consequently, peak splitting due to carbon-carbon spin-spin coupling is not observed in spectra. However, protons up to three sigma bonds away split the carbon signal according to the n+1 rule, resulting in complicated spectra.
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