一个具有光响应键的自锁分子
Takahiro Muraoka1, Kazushi Kinbara, Takuzo Aida
1Department of Chemistry and Biotechnology, School of Engineering, and Center for NanoBio Integration, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
Journal of the American Chemical Society
|August 31, 2006
概括
这项研究表明,在分子宿主中存在可逆自锁机制. 主机的主机的主机.
科学领域:
- 超分子化学 超分子化学
- 协调化学 协调化学
- 摄影化学的使用.
背景情况:
- 旋转宿主1具有铁素单元,并通过分子内Zn-N协调通过形态锁定.
- 这种内部锁定发生在色氨酸和氨酸单位之间的无极溶剂中.
研究的目的:
- 为了研究旋转宿主1和1,2-bispyridylethylene (2) 的异构体之间的宿主-客人相互作用.
- 通过光化学异构化控制的可逆自锁操作.
主要方法:
- 利用循环二元化 (CD) 光谱法可视化形状变化.
- 采用1,2-bispyridylethylene (cis-2和trans-2) 的 cis 和 trans 异构体作为客体.
- 研究了客分子的光化学异构化,以控制宿主的锁定状态.
主要成果:
- 这种cis同位素 (cis-2) 很容易分裂宿主内部的协调键,形成一个外部锁定的复合体.
- 转变异构体 (转变-2) 不会破坏内部锁定,显示不同的结合亲和力.
- cis-2到trans-2的光化学异构化释放了客体并恢复了内部锁.
- 在宿主的存在下,通过光化学异构化,将trans-2转化为cis-2,从而诱导外部锁定.
结论:
- 在分子系统中证明了可逆自锁操作.
- 突出了客体异构和光化学控制在超分子组装中的关键作用.
- 展示了响应光的分子机器和开关的潜力.
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