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Updated: Jul 12, 2026

In Situ Detection of Autoreactive CD4 T Cells in Brain and Heart Using Major Histocompatibility Complex Class II Dextramers
13:10

In Situ Detection of Autoreactive CD4 T Cells in Brain and Heart Using Major Histocompatibility Complex Class II Dextramers

Published on: August 1, 2014

在多发性硬化症中,T细胞识别一种免疫主导的髓基本蛋白质表位

K Ota1, M Matsui, E L Milford

  • 1Division of Neurology, Brigham and Women's Hospital, Boston, Massachusetts.

Nature
|July 12, 1990
PubMed
概括

研究人员确定了一个特定的髓基蛋白区域 (残留物84-102),该区域在多发性硬化症 (MS) 患者中更频繁地被T细胞准,特别是DR2表型患者. 这一发现可能解释了一些个体的多发性硬化病原体.

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Special Features of Adaptive Immunity

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Complete Antigens
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