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Updated: Jul 6, 2026

Assays for the Degradation of Misfolded Proteins in Cells
10:56

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Published on: August 28, 2016

神经退行性疾病蛋白质aprataxin解决了堕落的DNA结合中间体

Ivan Ahel1, Ulrich Rass, Sherif F El-Khamisy

  • 1Cancer Research UK, London Research Institute, Clare Hall Laboratories, South Mimms, Herts EN6 3LD, UK.

Nature
|September 12, 2006
PubMed
概括

阿普拉素解决了堕落的DNA结合,防止未经修复的DNA链断裂. 这一发现澄清了阿塔克西亚眼运动失调-1背后的机制,这是一种由APTX基因突变引起的神经疾病.

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