在孕前后胎儿和婴儿存活率的趋势
Olga Basso1, Svein Rasmussen, Clarice R Weinberg
1Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA. bassoo2@niehs.nih.gov
JAMA
|September 21, 2006
概括
产前的早期分娩改善了胎儿生存率,但没有改变新生儿死亡风险. 这项研究评估了因子宫前而增加的早产率对婴儿存活结果的影响.
科学领域:
- 产周医学 产周医学
- 产科 产科 产科 产科 产科
- 新生儿科学 新生儿科学
背景情况:
- 孕前管理通常涉及早产,增加早产婴儿的风险.
- 增加早产率对胎儿和婴儿存活率的净影响尚不清楚.
研究的目的:
- 评估预先分娩妊娠中早产率上升对胎儿和婴儿存活率的影响.
- 评估随着时间的推移与孕前相关的死产和新生儿死亡率的变化.
主要方法:
- 使用挪威登记数据 (1967-2003) 进行基于人口的观察性研究.
- 包括804,448个独生子初生的婴儿.
- 分析了胎儿和幼儿死亡的几率比率与妊娠前的关系.
主要成果:
- 在1967-1978年和1991-2003年期间,早产前的早期诱导 (在37周之前) 从8%增加到近20%,从1967-1978年到1991-2003年.
- 在先性怀孕中,死产风险 (OR) 从4.2显著降低到1.3.
- 新生儿死亡风险 (OR) 保持稳定 (1.7至2.0),晚期死亡率几乎没有变化.
结论:
- 由于积极的管理,在先性怀孕中胎儿存活率显著提高.
- 在研究期间,产前症后新生儿死亡的风险没有改善.
- 需要进一步的研究来解决持续的新生儿死亡风险.
相关概念视频
Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Fetal Circulation
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Pathophysiology of Diabetes
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...


