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Updated: May 5, 2026

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
07:12

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Published on: April 16, 2015

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孤儿核受体RORgammat指导促炎IL-17+ T辅助细胞的分化程序

Ivaylo I Ivanov1, Brent S McKenzie, Liang Zhou

  • 1Molecular Pathogenesis Program, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, 540 First Avenue, New York, NY 10016, USA.

Cell
|September 23, 2006
PubMed
概括

已确定RORgammat是驱动促炎性T辅助17 (Th17) 细胞发展的关键转录因子. 这一发现凸显了RORgammat作为自身免疫和炎症性疾病的潜在治疗点.

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Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation07:46

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